I-Manufactory Supply 114471-18-0 Nesiritide Acetate (BNP-32)99% powder omhlophe CAS NO.114471-18-0
Ingcaciso yeMveliso
I-Nesiritide Acetate (BNP-32) INOMBOLO YECAS: 114471-18-0
I-Nesiritide yi-brainnatriureticpeptide yomntu eyenziweyo (i-BNChemicalbookP) efunyenwe kwi-Escherichiacoli isebenzisa iteknoloji ye-DNA edibeneyo, kwaye umphumo wayo ufana kakhulu ne-BNP yomntu.Iqulethe i-32-amino acid polypeptide, edityaniswe yi-disulfide bond phakathi kwe-l0 kunye ne-26 ye-amino acid (zombini i-cysteine), eyenza i-ring equkethe i-l7 amino acids.
I-Nesiritide isebenza emva kokubophelela kwi-natriuretic peptide A kunye ne-B receptors.Ukongeza ekwandiseni imveliso ye-cGMP, i-nesilitide iphinde yehlisa umsebenzi we-renin-angiotensin system (RAS) kunye ne-nerve enovelwano.Inempembelelo ecacileyo yokwelula kuwo wonke umzimba we-arteriole kunye ne-venule.Inokunciphisa kakhulu uxinzelelo lwe-pulmonary capillary chock kunye ne-Chemicalbook right atrial pressure J, kunye nokunciphisa ukulayisha kwangaphambili kwentliziyo kwintliziyo.I-Nesiritide inokunciphisa kakhulu ukunyanzeliswa kwemithambo ye-peripheral, ukuze kuncitshiswe ukugcwala kwentliziyo emva kokungaphumeleli kwentliziyo.Inokunyusa isalathisi senhliziyo, kwaye indlela yayo ihambelana nokunciphisa emva komthwalo wenhliziyo.Inempembelelo ethile yokwandisa kwi-coronary artery.Kwakhona kunempembelelo yokunciphisa ukusetyenziswa kwe-oksijini ye-myocardial.
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